TGF-beta and cancer
PRINCIPAL INVESTIGATORS
- Angels Fabra Fres
- Javier Vaquero Rodríguez
- Elisa Maria Espinet Hernández
CLINICAL RESEARCHERS
- Teresa Serrano Piñol
- Emilio Ramos Rubio
- Mariona Calvo Campos
- Josep Ramón Ferreres Riera
POSTDOCTORAL RESEARCHERS
- Nicolás Peláez Llaneza
- Josep Amengual Segura
- Paula Segales Rovira
- Irene Peñuelas Haro
PREDOCTORAL RESEARCHERS
- Ana Cantos Cortes
- Gemma Gonfaus Ortiz
- Cristhian Ariel Acuña Pincay
- Rut Espinosa Sotelo
- Martin Jimenez Arriola
- Rosanna Scialpi
SCIENTIFIC SUPPORT
- Esther Bertran Rodriguez
Cancer
Oncobell
Scientific production
12
PAPERS
Average IF: 6,50
9
LED PAPERS
Average IF: 6,48
4 PUBLICATIONS IN FIRST DECILE
9 PUBLICATIONS IN FIRST QUARTILE
9 PUBLICATIONS IN OPEN ACCESS
Selected publications
- López Gil,JC;García Silva,S;Ruiz Cañas,L;Navarro,D;Palencia Campos,A;Giráldez Trujillo,A;Earl,J et al, The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells, Gut, 2024;73(9):1489-1508, doi:10.1136/gutjnl-2023-330995
- Amengual,J;Alay,A;Vaquero,J;Gonzalez Sanchez,E;Bertran,E;Sánchez,A;Herrera,B et al, Iron chelation as a new therapeutic approach to prevent senescence and liver fibrosis progression, Cell Death Dis., 2024;15(9):680-680, doi:10.1038/s41419-024-07063-0
- Gonzalez Sanchez,E;Vaquero,J;Caballero Diaz,D;Grzelak,J;Fusté,NP;Bertran,E;Amengual,J et al, The hepatocyte epidermal growth factor receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche, J. Pathol., 2024;263(4-5):482-495, doi:10.1002/path.6299
- Ferreres,JR;Vinyals,A;Campos Martin,R;Espín,R;Podlipnik,S;Ramos,R;Bertran,E et al, PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients, Mol. Oncol., 2024;18(10):2471-2494, doi:10.1002/1878-0261.13688
- Ramos,R;Vinyals,A;Campos Martin,R;Cabré,E;Bech,JJ;Vaquero,J;Gonzalez Sanchez,E et al, New Insights into the Exosome-Induced Migration of Uveal Melanoma Cells and the Pre-Metastatic Niche Formation in the Liver, Cancers, 2024;16(17):doi:10.3390/cancers16172977
Research highlights
PROJECTS
7 Ongoing competitive projects
1 Ongoing clinical trial
1 Ongoing non competitive project
PUBLISHED WORKS
1 Clinical guideline
2 Theses
INNOVATION
1 license
NETWORKS
CIBEREHD
COST action Precision BTC Network
AGAUR SGR GRC 2021
Selected projects
- PID2021-122551OB-I00. Descifrando el papel de la NADPH oxidasa NOX4 en el carcinoma hepatocelular: relevancia en células tumorales y estroma y relación con la vía del TGF-beta. Ministerio de Ciencia e Innovación. Budget: 344.850€. 2022-2025. PI: FABREGAT ROMERO, MARIA ISABEL.
- TRANSCAN2021-237/AC22/00034. Targeting ROBOs and SLIT guidance cues in the immunosuppressive stromal context of pancreatic cancer (TRanSLIT). Instituto de Salud Carlos III (ISCIII)/ Asociación Española Contra el Cáncer (AECC). Budget: 302.600#. 2023-2025. PI: Espinet Hernández, Elisa Maria.
- PRYGN211279FABR. Towards a precision medicine using TGF-ß inhibitors in hepatocellular carcinoma and cholangiocarcinoma. Asociación Española Contra el Cáncer (AECC). Budget: 299.813,75.€ 2021-2025. PI: FABREGAT ROMERO, MARIA ISABEL.
- PRE2022-101761. AYUDAS PARA CONTRATOS PREDOCTORALES PARA LA FORMACIÓN DE DOCTORES 2022. Ministerio de Ciencia e Innovación. Budget: 111.758€. 2023-2027. PI: FABREGAT ROMERO, MARIA ISABEL.
- Dissecting the role of the hepatocyte Epidermal Growth Factor Receptor (EGFR) pathway in the cellular interactome within the liver fibrotic niche. FUNDACIÓN RAMÓN ARECES. Budget: 112.000€. 2021-2024. PI: FABREGAT ROMERO, MARIA ISABEL.